SS-31
Elamipretide · D-Arg-Dmt-Lys-Phe-NH2 · Bendavia
A cardiolipin-targeted mitochondria-protective peptide showing remarkable results in heart failure, AMD, and mitochondrial disease research.
Half-Life
~2-3 hours
MW
639.8 Da
Amino Acids
4 AA
Evidence
Moderate Evidence
Regulatory Status
Phase II/III clinical trials for heart failure and AMD. Not yet approved.
In Plain English
A tiny peptide that specifically homes to and protects the inner membrane of your mitochondria — the most damage-prone part of your cellular power plants. Shown in human trials to help heart and kidney function.
Overview
SS-31 (Elamipretide) is a cell-permeable aromatic-cationic tetrapeptide that selectively targets the inner mitochondrial membrane lipid cardiolipin. It has demonstrated significant improvements in mitochondrial function, heart failure, age-related macular degeneration, and mitochondrial disease trials.
Common Formats
- Lyophilized powder (injectable)
Storage Notes
-20°C lyophilized.
Looking for multi-compound protocols?
Browse educational protocol discussions that include SS-31.
Related Compounds
MOTS-c
A mitochondrial-derived peptide that regulates metabolic homeostasis, glucose uptake, and has shown remarkable longevity effects in animal studies.
Humanin
A mitochondria-derived peptide encoded in the 16S rRNA region with remarkable cytoprotective, anti-apoptotic, and longevity-associated properties.
Epitalon
A synthetic tetrapeptide based on Epithalamin with telomerase activation and antioxidant properties showing remarkable longevity effects in multiple animal species.
Educational Disclaimer: All information on this page is for educational and research purposes only. This does not constitute medical advice, diagnosis, or treatment recommendation. Consult a qualified healthcare professional.