Epitalon
Epithalamin · Epithalone · Tetrapeptide AEDG
A synthetic tetrapeptide based on Epithalamin with telomerase activation and antioxidant properties showing remarkable longevity effects in multiple animal species.
Half-Life
~30-60 minutes
MW
390.4 Da
Amino Acids
4 AA
Evidence
Moderate Evidence
Regulatory Status
Research compound. Decades of use history in Russia/Eastern Europe.
In Plain English
A 4-amino acid peptide from the pineal gland that activates telomerase — the enzyme that rebuilds the end-caps on your chromosomes. Each cell division shortens these caps; research suggests Epitalon can partially reverse this aging clock.
Overview
Epitalon (Ala-Glu-Asp-Gly) is a synthetic tetrapeptide based on the natural polypeptide Epithalamin extracted from the pineal gland. It has been studied extensively at the Institute of Gerontology in St. Petersburg since the 1980s. Remarkable research suggests telomerase activation, telomere elongation, and lifespan extension in multiple species.
Common Formats
- Lyophilized powder (injectable)
- Nasal spray
- Oral (reduced bioavailability)
Storage Notes
-20°C lyophilized. 4°C reconstituted.
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Related Compounds
GHK-Cu
A naturally occurring copper complex peptide with potent wound healing, anti-aging, and regenerative properties studied extensively for skin and tissue applications.
MOTS-c
A mitochondrial-derived peptide that regulates metabolic homeostasis, glucose uptake, and has shown remarkable longevity effects in animal studies.
DSIP
A naturally occurring neuropeptide that regulates sleep-wake cycles, stress response, and has shown longevity-associated effects in animal research.
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