Ipamorelin
NNC-26-0161
A highly selective GH secretagogue and ghrelin receptor agonist known for clean GH release without significant cortisol or prolactin stimulation.
Half-Life
~2 hours
MW
711.86 Da
Amino Acids
5 AA
Evidence
Moderate Evidence
Regulatory Status
Research compound. FDA-approved trials for GI motility disorders (different indication).
In Plain English
Tells your pituitary gland to release growth hormone in a clean, controlled pulse — like pressing exactly the right button. Won't spike cortisol or hunger like older GH secretagogues. The "beginner-friendly" option in the GH peptide world.
Overview
Ipamorelin is a pentapeptide ghrelin receptor agonist (GH secretagogue) that selectively stimulates GH release from the pituitary. It is valued for its selectivity — stimulating GH without significantly affecting cortisol, prolactin, or other hormones, making it one of the most targeted GH release peptides available.
Common Formats
- Lyophilized powder (injectable)
Storage Notes
-20°C lyophilized. Reconstituted 4°C, 4-6 weeks.
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Related Compounds
CJC-1295
A long-acting GHRH analogue with a Drug Affinity Complex that extends its half-life dramatically, allowing weekly dosing for sustained GH elevation.
Sermorelin
A 29-amino acid truncated analogue of endogenous GHRH, FDA-approved for pediatric GHD and widely researched for anti-aging and body composition.
GHRP-2
A potent GH secretagogue with strong ghrelin receptor activity, producing significant GH pulses with some cortisol and prolactin elevation.
Hexarelin
The most potent GH secretagogue peptide available, with additional direct cardiac and anti-fibrotic research applications.
Educational Disclaimer: All information on this page is for educational and research purposes only. This does not constitute medical advice, diagnosis, or treatment recommendation. Consult a qualified healthcare professional.