CJC-1295
CJC-1295 DAC · DAC:GRF · Drug Affinity Complex Growth Releasing Factor
A long-acting GHRH analogue with a Drug Affinity Complex that extends its half-life dramatically, allowing weekly dosing for sustained GH elevation.
Half-Life
~8 days (DAC version), ~30 min (no-DAC version)
MW
3647.3 Da
Amino Acids
30 AA
Evidence
Moderate Evidence
Regulatory Status
Research compound. Not approved for clinical use.
In Plain English
A long-lasting version of the signal your brain uses to tell your body to make growth hormone. One injection keeps GH pulses elevated for days instead of minutes. The DAC version is the long-acting form that lasts ~2 weeks.
Overview
CJC-1295 is a tetrasubstituted 30-amino acid peptide hormone analogue of GHRH. The DAC (Drug Affinity Complex) version binds to albumin in the blood, extending its half-life from minutes to approximately 8 days. This allows for less frequent dosing while maintaining elevated GH and IGF-1 levels.
Common Formats
- Lyophilized powder (injectable)
Storage Notes
Lyophilized: -20°C up to 2 years. Reconstituted: 4°C, use within 4-6 weeks.
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Related Compounds
Ipamorelin
A highly selective GH secretagogue and ghrelin receptor agonist known for clean GH release without significant cortisol or prolactin stimulation.
Sermorelin
A 29-amino acid truncated analogue of endogenous GHRH, FDA-approved for pediatric GHD and widely researched for anti-aging and body composition.
GHRP-2
A potent GH secretagogue with strong ghrelin receptor activity, producing significant GH pulses with some cortisol and prolactin elevation.
GHRP-6
One of the original GH secretagogue peptides, notable for strong hunger stimulation alongside robust GH release.
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