Cortagen
Ala-Glu-Asp-Pro · AEDP tetrapeptide · Pulmonary bioregulator
A synthetic tetrapeptide bioregulator derived from lung tissue, developed in the Russian peptide bioregulator program, studied for lung tissue regeneration, anti-inflammatory properties, and anti-aging effects in the bronchopulmonary system.
Half-Life
Very short (minutes) — like other tetrapeptide bioregulators.
MW
414.38 Da
Amino Acids
4 AA
Evidence
Experimental
Regulatory Status
Research compound. Not approved by FDA or EMA. Developed in Russian bioregulator research context.
In Plain English
A four-amino-acid signal extracted from lung tissue, studied for whether it can help aging lungs repair and maintain themselves. Part of a broader Russian research program that identified tiny peptide signals from each organ and studied whether supplementing them could slow age-related organ decline.
Overview
Cortagen is a synthetic tetrapeptide (Ala-Glu-Asp-Pro) identified as the active bioregulator fraction of lung tissue extract in the Russian peptide bioregulator research program (Khavinson et al.). Like Epithalon (pineal), Thymalin (thymus), and Vilon (thymus dipeptide), Cortagen is one of a series of organ-specific bioregulators studied for their ability to normalise gene expression in aging tissues. It has been primarily studied in the context of lung tissue regeneration, age-related pulmonary function decline, and COPD-adjacent research.
Common Formats
- Lyophilized powder (injectable)
- Oral research form
Storage Notes
Store lyophilized at -20°C. Reconstituted: refrigerate and use within days.
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Related Compounds
Vilon
A synthetic dipeptide (Lys-Glu) derived from the thymus with studied immunomodulatory and longevity-associated properties, developed as part of the Russian bioregulator peptide program.
Epitalon
A synthetic tetrapeptide based on Epithalamin with telomerase activation and antioxidant properties showing remarkable longevity effects in multiple animal species.
Thymalin
Polypeptide extract from the thymus gland that broadly restores immune function and extends longevity in research.
LL-37
The only human cathelicidin antimicrobial peptide, with broad-spectrum antimicrobial activity, immunomodulation, and wound-healing properties.
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