LL-37
Cathelicidin LL-37 · CAP-18 · hCAP18/LL-37
The only human cathelicidin antimicrobial peptide, with broad-spectrum antimicrobial activity, immunomodulation, and wound-healing properties.
Half-Life
~2-3 hours
MW
4493.3 Da
Amino Acids
37 AA
Evidence
Moderate Evidence
Regulatory Status
Research compound. Topical applications in clinical trials.
In Plain English
Your body's own natural antibiotic peptide — one of the front-line defenders against bacteria, fungi, and viruses. It also signals immune cells to the infection site and helps wounds close. Low LL-37 is linked to recurring infections.
Overview
LL-37 is derived from hCAP-18, the only human cathelicidin. It is a cationic, alpha-helical peptide with potent antimicrobial activity against bacteria, viruses, and fungi. It also has immunomodulatory and wound-healing properties, making it important in host defense.
Common Formats
- Lyophilized powder (injectable)
- Topical (research)
Storage Notes
-20°C lyophilized. 4°C reconstituted, 1-2 weeks.
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Related Compounds
Thymosin Alpha-1
A 28-amino acid peptide derived from the thymus with potent immunomodulatory effects approved in multiple countries for hepatitis and cancer supportive care.
BPC-157
A 15 amino acid peptide derived from human gastric juice, widely researched for its tissue-healing and cytoprotective properties.
Educational Disclaimer: All information on this page is for educational and research purposes only. This does not constitute medical advice, diagnosis, or treatment recommendation. Consult a qualified healthcare professional.