Thymosin Beta-4 (TB-4)
Tβ4 · Full-length TB-4 · TB-500 parent compound
The full 43-amino acid endogenous thymic peptide from which TB-500 is derived — with additional regenerative and cardiac repair properties.
Half-Life
~6–8 hours
MW
N/A
Amino Acids
N/A
Evidence
Clinical
Regulatory Status
Clinical trials (cardiac repair); TB-500 analog in research
In Plain English
The full version of the TB-500 peptide — your body actually makes this. TB-500 is a synthetic copy of its most active sequence. TB-4 does everything TB-500 does, plus has unique cardiac stem cell activation properties studied after heart attacks.
Overview
Thymosin Beta-4 (Tβ4) is the full 43-amino acid endogenous peptide produced by the thymus from which the synthetic fragment TB-500 (Ac-SDKP... the active 17-amino acid sequence) is derived. TB-4 has all the properties of TB-500 plus additional functions including cardiac progenitor cell activation and broader actin-binding activities. Research in cardiac regeneration following myocardial infarction has been particularly notable. TB-4 is the endogenous molecule; TB-500 is a synthesized fragment approximating its activity.
Common Formats
- Injectable (subcutaneous)
- Injectable (intramuscular)
Storage Notes
Refrigerate. Reconstituted: use within 30 days refrigerated.
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Related Compounds
TB-500
A synthetic version of the naturally occurring peptide Thymosin Beta-4, studied for tissue repair, inflammation reduction, and vascular remodeling.
BPC-157
A 15 amino acid peptide derived from human gastric juice, widely researched for its tissue-healing and cytoprotective properties.
GHK-Cu
A naturally occurring copper complex peptide with potent wound healing, anti-aging, and regenerative properties studied extensively for skin and tissue applications.
SS-31
A cardiolipin-targeted mitochondria-protective peptide showing remarkable results in heart failure, AMD, and mitochondrial disease research.
Educational Disclaimer: All information on this page is for educational and research purposes only. This does not constitute medical advice, diagnosis, or treatment recommendation. Consult a qualified healthcare professional.