N-Acetyl Semax
NA Semax · Acetylated Semax · N-Ac Semax
An acetylated derivative of Semax with enhanced potency and potentially more consistent activity compared to the parent compound, studied for cognitive enhancement and neuroprotection.
Half-Life
Slightly extended vs. Semax due to N-terminal protection. Estimated hours (intranasal).
MW
~960 Da
Amino Acids
7 AA
Evidence
Experimental
Regulatory Status
Research compound. Not approved by FDA or EMA. Developed from Russian pharmacological research.
In Plain English
Regular Semax with a protective acetyl cap added to one end. The cap stops enzymes from chewing up the peptide too quickly, so it lasts longer and hits stronger at lower doses. Think of it as Semax with a reinforced molecular shell.
Overview
N-Acetyl Semax is a modified version of Semax where an acetyl group is added to the N-terminus of the peptide chain. This acetylation protects the peptide from enzymatic degradation at the N-terminal end, potentially extending its activity and bioavailability compared to regular Semax. Users and researchers report it as more potent on a per-microgram basis, though direct comparative human studies are limited. Like Semax, it is primarily used intranasally.
Common Formats
- Intranasal solution (research)
- Lyophilized powder
Storage Notes
Store lyophilized at -20°C. Intranasal solution: refrigerate, use within weeks of preparation.
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Related Compounds
Semax
A synthetic heptapeptide based on ACTH fragment with potent nootropic, neuroprotective, and stroke-recovery properties developed in Russia.
N-Acetyl Selank
An acetylated derivative of Selank with enhanced stability and potentially greater anxiolytic and nootropic activity compared to the parent compound.
Selank
A synthetic heptapeptide analogue of tuftsin with anxiolytic, nootropic, and immune-modulating properties developed in Russia.
Dihexa
An extremely potent nootropic peptide (10 million times more potent than BDNF) that enhances synaptogenesis, with promising research in Alzheimer's models.
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