Melanotan II
MT-2 · MT-II · Melanotan 2
A cyclic alpha-MSH analogue with potent melanogenic, sexual arousal, and appetite-suppressing effects through broad melanocortin receptor activation.
Half-Life
~30 min to 1 hour
MW
1024.2 Da
Amino Acids
7 AA
Evidence
Low Evidence
Regulatory Status
Not approved. Research compound only. Not recommended for use due to safety concerns.
In Plain English
A cyclic, more potent version of MT-I that causes tanning plus sexual arousal effects. Stronger but also more side effects — nausea and spontaneous erections are common. Not approved for any use.
Overview
Melanotan II is a cyclic analogue of alpha-MSH with higher CNS penetration and broader receptor activity than MT-I. It activates MC1R (tanning), MC3R (energy regulation), MC4R (sexual function, appetite), and MC5R. Not FDA-approved.
Common Formats
- Lyophilized powder (research)
Storage Notes
-20°C lyophilized. Light sensitive.
Looking for multi-compound protocols?
Browse educational protocol discussions that include Melanotan II.
Related Compounds
Melanotan I
A synthetic alpha-MSH analogue with FDA-orphan drug approval for erythropoietic protoporphyria, producing skin darkening through melanin stimulation.
PT-141
FDA-approved melanocortin receptor agonist for hypoactive sexual desire disorder in premenopausal women, with off-label research in men.
Educational Disclaimer: All information on this page is for educational and research purposes only. This does not constitute medical advice, diagnosis, or treatment recommendation. Consult a qualified healthcare professional.