Ac-SDKP
N-acetyl-Ser-Asp-Lys-Pro · Goralatide
Endogenous tetrapeptide that inhibits fibrosis, suppresses bone marrow suppression during chemotherapy, and has anti-inflammatory effects.
Half-Life
~5–10 minutes (rapidly cleaved by ACE); stable in ACE-inhibitor context
MW
N/A
Amino Acids
N/A
Evidence
Preclinical
Regulatory Status
Research compound
In Plain English
A naturally occurring tetrapeptide in your blood that fights organ scarring and protects stem cells during chemotherapy. Your ACE enzyme constantly destroys it; taking ACE inhibitor drugs actually raises your Ac-SDKP levels as a bonus effect.
Overview
Ac-SDKP (N-acetyl-Ser-Asp-Lys-Pro) is a naturally occurring tetrapeptide found in blood and various tissues, particularly concentrated in bone marrow. It is a natural substrate of ACE (angiotensin-converting enzyme). Research shows it inhibits fibrosis in the heart, kidneys, and liver; protects hematopoietic stem cells; and modulates inflammatory responses. Gaining interest as an anti-fibrotic and chemoprotective agent.
Common Formats
- Injectable (subcutaneous)
- Injectable (intravenous in research)
Storage Notes
Refrigerate or freeze. Stable in solution for shorter periods.
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Related Compounds
BPC-157
A 15 amino acid peptide derived from human gastric juice, widely researched for its tissue-healing and cytoprotective properties.
TB-500
A synthetic version of the naturally occurring peptide Thymosin Beta-4, studied for tissue repair, inflammation reduction, and vascular remodeling.
GHK-Cu
A naturally occurring copper complex peptide with potent wound healing, anti-aging, and regenerative properties studied extensively for skin and tissue applications.
Educational Disclaimer: All information on this page is for educational and research purposes only. This does not constitute medical advice, diagnosis, or treatment recommendation. Consult a qualified healthcare professional.