Half-Life Calculator

Serum level curves & clearance modeling

Models first-order exponential decay based on published or estimated half-life values. Real serum concentrations vary with individual pharmacokinetics, route, injection site, and metabolism. Use for educational reference only — these are theoretical curves, not clinical data.

Compound 1

= 0.25 mg

Peak level
282.4 mcg
SS accumulation
×1.14
90% cleared
13h
SS in ~
17h

Serum Level Curve

BPC-157
0m1.9d3.8d5.8d7.7d141.2 mcg282.4 mcg
X-axis: time from first doseY-axis: estimated relative serum level| marks: injection times

Clearance Reference

BPC-157 — t½ = 4.0h

50% cleared
4.0h
after dose
75% cleared
8.0h
after dose
90% cleared
13h
after dose
95% cleared
17h
after dose
99% cleared
1.1d
after dose
Steady-state accumulation at 12h dosing:×1.14(peak ~ 285.7 mcg) — reached in ~17h

About Half-Life Calculations

This calculator models first-order exponential decay, the standard pharmacokinetic model for most peptides. The formula used is: C(t) = C₀ × e^(-λt), where λ = ln(2) / t½.

Accumulation occurs when the dosing interval is shorter than the time needed for full clearance. At steady state, the peak level is the single-dose peak multiplied by the accumulation factor: 1 / (1 − e^(−λ × interval)).

Half-life values shown in presets are literature-derived estimates for subcutaneous administration where available. Actual values vary with individual metabolism, body composition, injection depth, and other factors.