Exenatide
Byetta ยท Bydureon ยท Exendin-4
The first GLP-1 receptor agonist approved by the FDA for T2D, derived from Gila monster venom with strong glucose-lowering and weight management effects.
Half-Life
~2.4 hours (exenatide), ~2 weeks (extended release)
MW
4186.6 Da
Amino Acids
39 AA
Evidence
High Evidence
Regulatory Status
FDA-approved (Byetta: twice daily, Bydureon: weekly).
Research reference values only. Confirm all parameters with current literature and your clinician.
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Related Compounds
Semaglutide
A GLP-1 receptor agonist with FDA approval for type 2 diabetes and obesity, demonstrating unprecedented weight loss results in clinical trials.
Liraglutide
A once-daily GLP-1 receptor agonist with FDA approval for T2D and obesity, the predecessor to semaglutide with strong clinical evidence.
Tirzepatide
A dual GIP/GLP-1 receptor agonist with FDA approval showing up to 22% weight loss โ superior to semaglutide in head-to-head trials.
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